Quarterly report pursuant to Section 13 or 15(d)

Quarterly report pursuant to Section 13 or 15(d)

Equity - Summary of Stock-Based Compensation Expense Recognized for Stock Options and Restricted Stock Included in Consolidated Statements of Operations (Detail)

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Equity - Summary of Stock-Based Compensation Expense Recognized for Stock Options and Restricted Stock Included in Consolidated Statements of Operations (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Stock based compensation expense $ 2,333 $ 1,922 $ 3,957 $ 3,052
Research and development expense        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Stock based compensation expense 251 285 269 327
General and administrative expense        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Stock based compensation expense $ 2,082 $ 1,637 $ 3,688 $ 2,725