Annual report pursuant to Section 13 and 15(d)

Acquisitions - Narrative (Details)

Acquisitions - Narrative (Details) - USD ($)				1 Months Ended	6 Months Ended	12 Months Ended
Acquisitions - Narrative (Details) - USD ($)	Sep. 30, 2021	Jun. 18, 2021	Apr. 07, 2021	Apr. 30, 2021	Dec. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Mar. 31, 2022	May 31, 2020	May 22, 2020
Business Acquisition [Line Items]
Cash paid at closing						$ 0	$ 419,404,000	$ 37,000,000
Common stock, par value (in dollars per share)			$ 0.001		$ 0.001	$ 0.001	$ 0.001
Gain on investment in and loan receivable from non-consolidated affiliate, net						$ 0	$ 109,260,000	3,955,000
Affiliated Entity
Business Acquisition [Line Items]
Amount outstanding under line of credit		$ 10,300,000
Variable Interest Entity, Not Primary Beneficiary \| Affiliated Entity
Business Acquisition [Line Items]
Investment in minority interest		29,600,000							$ 29,600,000	$ 25,000,000	$ 25,000,000
Consideration paid to other shareholders		390,000,000
Identifiable intangible assets - developed technology \| Maximum
Business Acquisition [Line Items]
Amortization period (in years)						15 years	15 years
Marketing Assets
Business Acquisition [Line Items]
Amortization period (in years)						4 years	4 years
Trademarks
Business Acquisition [Line Items]
Amortization period (in years)						15 years	15 years
Trade Name
Business Acquisition [Line Items]
Amortization period (in years)						2 years 6 months	5 years
Trapelo Health
Business Acquisition [Line Items]
Voting interests acquired (as a percent)			100.00%
Cash paid at closing			$ 35,591,000
Payments to acquire business, adjustments			600,000
Fair value of common stock at Trapelo Acquisition Date			$ 29,174,000
Common stock issued (in shares)			597,712	597,712
Share price (in dollars per share)			$ 48.81
Amortization period (in years)			9 years 9 months 18 days
Goodwill, expected tax deductible amount			$ 0
Acquisition and integration costs						$ 0	$ 1,800,000	0
Trapelo Health \| Identifiable intangible assets - developed technology
Business Acquisition [Line Items]
Intangible assets, useful life (in years)			10 years
Trapelo Health \| Marketing Assets
Business Acquisition [Line Items]
Intangible assets, useful life (in years)			4 years
Inivata
Business Acquisition [Line Items]
Cash paid at closing		398,594,000
Payments to acquire business, adjustments		$ 8,600,000
Amortization period (in years)		14 years 10 months 24 days
Goodwill, expected tax deductible amount		$ 0
Acquisition and integration costs						0	13,900,000	0
Fair value of line of credit		15,000,000
Fair value of previously-held equity interest	$ 64,900,000	64,906,000
Fair value of purchase option	$ 74,300,000	74,300,000
Gain on investment in and loan receivable from non-consolidated affiliate, net						109,300,000	$ 109,300,000	$ 4,000,000
Deferred income tax liabilities		$ (56,645,000)
Revenue from acquiree					$ 1,500,000
Net loss from acquiree					$ 27,600,000
Acquisition related costs						11,000,000
Inivata \| Clinical Services
Business Acquisition [Line Items]
Goodwill acquired						234,600,000
Inivata \| Pharma Services
Business Acquisition [Line Items]
Goodwill acquired						$ 32,400,000
Inivata \| Identifiable intangible assets - developed technology \| Maximum
Business Acquisition [Line Items]
Intangible assets, useful life (in years)		15 years
Inivata \| Trademarks \| Maximum
Business Acquisition [Line Items]
Intangible assets, useful life (in years)		15 years
Inivata \| Trade Name
Business Acquisition [Line Items]
Intangible assets, useful life (in years)		5 years