Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - Additional Information (Detail)

v3.3.1.900
Commitments and Contingencies - Additional Information (Detail)
12 Months Ended
Dec. 31, 2015
USD ($)
ft²
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Commitments And Contingencies Disclosure [Abstract]      
Operating leases expiration period 2020-12    
Square Feet of Office and Laboratory | ft² 49,000    
Rent expenses $ 1,900,000 $ 1,700,000 $ 1,100,000
Purchase commitments expiration period 2019-10    
Capital lease expiration year 2019    
Weighted Average Interest Rates 8.04%    
Base salaries expected in 2016 $ 2,147,000