Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Investment in Non-Consolidated Affiliate (Details)

v3.22.4
Investment in Non-Consolidated Affiliate (Details)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 30, 2021
USD ($)
Jun. 18, 2021
USD ($)
May 22, 2020
USD ($)
board_seat
Mar. 31, 2021
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Mar. 31, 2022
USD ($)
May 22, 2021
USD ($)
Jan. 31, 2021
USD ($)
May 31, 2020
USD ($)
Schedule of Equity Method Investments [Line Items]                      
Carrying amount of investment in non-consolidated affiliate         $ 1,740,034 $ 1,869,778          
Gain on settlement under line of credit           4,700          
Gain on investment in and loan receivable from non-consolidated affiliate, net         0 109,260 $ 3,955        
Inivata                      
Schedule of Equity Method Investments [Line Items]                      
Fair value of previously-held equity interest $ 64,900 $ 64,906                  
Fair value of Purchase Option $ 74,300 74,300                  
Unrealized gain on investment in non-consolidated affiliate, net         104,600            
Gain on investment in and loan receivable from non-consolidated affiliate, net         $ 109,300 109,300 4,000        
Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Carrying amount of investment in non-consolidated affiliate             29,600        
Unrealized gain on remeasurement             4,000        
Preference Shares | Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Carrying amount of investment in non-consolidated affiliate             25,000        
Investment in non-consolidated affiliate                   $ 30,000  
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.0017            
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.840            
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.000            
Purchase Option | Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Carrying amount of investment in non-consolidated affiliate             $ 4,600        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.0017   0.0017        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.840   0.840        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate                      
Schedule of Equity Method Investments [Line Items]                      
Purchase option, measurement input (as a percent)         0.000   0.000        
Affiliated Entity                      
Schedule of Equity Method Investments [Line Items]                      
Net unrealized loss from remeasurement of investment       $ 5,000              
Amount outstanding under line of credit   10,300                  
Affiliated Entity | Line of Credit                      
Schedule of Equity Method Investments [Line Items]                      
Line of credit facility maximum borrowing capacity     $ 15,000           $ 15,000    
Interest rate per annum (as a percent)         0.00%            
Imputed interest rate (as a percent)                   8.33%  
Loan with imputed interest, discount)                   $ 5,000  
Additional investment in non-consolidated affiliate                   5,000  
Present value of loan receivable with imputed interest                   $ 10,000  
Amount outstanding under line of credit   10,300                  
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Investment in minority interest   29,600 $ 25,000         $ 29,600     $ 25,000
Number of board seats granted | board_seat     1                
Percentage of investment in equity (as a percent)         20.00%            
Transaction costs     $ 600                
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary | Line of Credit                      
Schedule of Equity Method Investments [Line Items]                      
Interest income from loan receivable           $ 400          
Affiliated Entity | Preference Shares | Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Investment in minority interest   25,000 19,600         25,000      
Affiliated Entity | Purchase Option | Variable Interest Entity, Not Primary Beneficiary                      
Schedule of Equity Method Investments [Line Items]                      
Investment in minority interest   $ 4,600 $ 6,000         $ 4,600