Quarterly report pursuant to Section 13 or 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Cumulative-effect adjustment from change in accounting principle	Common Stock	Additional Paid-In Capital	Additional Paid-In Capital Cumulative-effect adjustment from change in accounting principle	Accumulated Other Comprehensive (Loss) Income	(Accumulated Deficit) Retained Earnings	(Accumulated Deficit) Retained Earnings Cumulative-effect adjustment from change in accounting principle
Beginning balance (in shares) at Dec. 31, 2020			112,075,474
Beginning balance at Dec. 31, 2020	$ 694,294	$ (22,575)	$ 112	$ 701,357	$ (23,271)	$ 10	$ (7,185)	$ 696
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Premiums paid for capped call confirmations	(29,291)			(29,291)
Common stock issuance ESPP Plan (in shares)			23,917
Common stock issuance ESPP Plan	1,024			1,024
Issuance of restricted stock, net of forfeitures (in shares)			83,220
Issuance of restricted stock, net of forfeitures	(614)			(614)
Issuance of common stock for stock options (in shares)			260,167
Issuance of common stock for stock options	2,239			2,239
Issuance of common stock - public offering, net of underwriting discounts & private placement, net of private placement fees (in shares)			4,693,876
Issuance of common stock - public offering, net of underwriting discounts & private placement, net of private placement fees	218,500		$ 5	218,495
Stock issuance fees and expenses	(242)			(242)
ESPP expense	241			241
Stock-based compensation expense - options and restricted stock	2,412			2,412
Net unrealized loss on marketable securities, net of tax	(160)					(160)
Net (loss) income	(22,114)						(22,114)
Ending balance (in shares) at Mar. 31, 2021			117,136,654
Ending balance at Mar. 31, 2021	843,714		$ 117	872,350		(150)	(28,603)
Beginning balance (in shares) at Dec. 31, 2020			112,075,474
Beginning balance at Dec. 31, 2020	694,294	$ (22,575)	$ 112	701,357	$ (23,271)	10	(7,185)	$ 696
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net unrealized loss on marketable securities, net of tax	(343)
Net (loss) income	53,759
Ending balance (in shares) at Jun. 30, 2021			122,711,352
Ending balance at Jun. 30, 2021	1,148,358		$ 123	1,101,298		(333)	47,270
Beginning balance (in shares) at Mar. 31, 2021			117,136,654
Beginning balance at Mar. 31, 2021	843,714		$ 117	872,350		(150)	(28,603)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock issuance ESPP Plan (in shares)			31,839
Common stock issuance ESPP Plan	1,245			1,245
Issuance of restricted stock, net of forfeitures (in shares)			146,392
Issuance of restricted stock, net of forfeitures	(163)			(163)
Issuance of common stock for stock options (in shares)			354,310
Issuance of common stock for stock options	4,430		$ 1	4,429
Issuance of common stock - public offering, net of underwriting discounts & private placement, net of private placement fees (in shares)			4,444,445
Issuance of common stock - public offering, net of underwriting discounts & private placement, net of private placement fees	189,863		$ 4	189,859
Issuance of common stock for acquisition (in shares)			597,712
Issuance of common stock for acquisition	29,175		$ 1	29,174
Stock issuance fees and expenses	(102)			(102)
ESPP expense	298			298
Stock-based compensation expense - options and restricted stock	4,208			4,208
Net unrealized loss on marketable securities, net of tax	(183)					(183)
Net (loss) income	75,873						75,873
Ending balance (in shares) at Jun. 30, 2021			122,711,352
Ending balance at Jun. 30, 2021	1,148,358		$ 123	1,101,298		(333)	47,270
Beginning balance (in shares) at Dec. 31, 2021			124,107,500
Beginning balance at Dec. 31, 2021	1,108,277		$ 124	1,123,628		(638)	(14,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock issuance ESPP Plan (in shares)			47,853
Common stock issuance ESPP Plan	971			971
Issuance of restricted stock, net of forfeitures (in shares)			100,253
Issuance of restricted stock, net of forfeitures	(1,049)			(1,049)
Issuance of common stock for stock options (in shares)			466,609
Issuance of common stock for stock options	6,480		$ 1	6,479
ESPP expense	249			249
Stock-based compensation expense - options and restricted stock	11,855			11,855
Net unrealized loss on marketable securities, net of tax	(2,371)					(2,371)
Net (loss) income	(49,408)						(49,408)
Ending balance (in shares) at Mar. 31, 2022			124,722,215
Ending balance at Mar. 31, 2022	1,075,004		$ 125	1,142,133		(3,009)	(64,245)
Beginning balance (in shares) at Dec. 31, 2021			124,107,500
Beginning balance at Dec. 31, 2021	$ 1,108,277		$ 124	1,123,628		(638)	(14,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock for stock options (in shares)	566,583
Net unrealized loss on marketable securities, net of tax	$ (3,418)
Net (loss) income	(84,711)
Ending balance (in shares) at Jun. 30, 2022			125,679,573
Ending balance at Jun. 30, 2022	1,043,519		$ 126	1,146,997		(4,056)	(99,548)
Beginning balance (in shares) at Mar. 31, 2022			124,722,215
Beginning balance at Mar. 31, 2022	1,075,004		$ 125	1,142,133		(3,009)	(64,245)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock issuance ESPP Plan (in shares)			89,374
Common stock issuance ESPP Plan	807			807
Issuance of restricted stock, net of forfeitures (in shares)			773,010
Issuance of restricted stock, net of forfeitures	(310)		$ 1	(311)
Issuance of common stock for stock options (in shares)			94,974
Issuance of common stock for stock options	743		$ 0	743
ESPP expense	293			293
Stock-based compensation expense - options and restricted stock	3,332			3,332
Net unrealized loss on marketable securities, net of tax	(1,047)					(1,047)
Net (loss) income	(35,303)						(35,303)
Ending balance (in shares) at Jun. 30, 2022			125,679,573
Ending balance at Jun. 30, 2022	$ 1,043,519		$ 126	$ 1,146,997		$ (4,056)	$ (99,548)