Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Subsequent Events (Details)

v3.20.4
Subsequent Events (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 06, 2021
Jun. 03, 2020
Apr. 29, 2020
May 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Jan. 11, 2021
May 22, 2020
Subsequent Event [Line Items]                  
Number of shares issued in transaction       8,100,000          
Common stock, par value (in dollars per share)         $ 0.001 $ 0.001      
Sale of stock, price per share (in dollars per share)       $ 21.25          
Sale of stock, consideration received       $ 160,800,000          
Proceeds from issuance of convertible debt, net of issuance costs         $ 194,466,000 $ 0 $ 0    
Strategic Alliance With Inivata Limited | Affiliated Entity                  
Subsequent Event [Line Items]                  
Stated interest rate (as a percent)                 0.00%
Line of credit facility maximum borrowing capacity                 $ 15,000,000
Common Stock Offering                  
Subsequent Event [Line Items]                  
Number of shares issued in transaction     4,400,000            
Common stock, par value (in dollars per share)     $ 0.001            
Sale of stock, price per share (in dollars per share)     $ 28.50            
Sale of stock, consideration received     $ 117,900,000            
Over-Allotment Option                  
Subsequent Event [Line Items]                  
Number of shares issued in transaction   351,500 660,000            
Sale of stock, consideration received   $ 9,400,000              
Subsequent Event | Convertible Senior Notes Due 2028                  
Subsequent Event [Line Items]                  
Stated interest rate (as a percent) 0.25%                
Debt instrument, face amount $ 300,000,000                
Optional additional face amount $ 45,000,000                
Discount on principal (as a percent) 97.00%                
Proceeds from issuance of convertible debt, net of issuance costs $ 334,500,000                
Subsequent Event | Common Stock Offering                  
Subsequent Event [Line Items]                  
Number of shares issued in transaction 4,081,632                
Common stock, par value (in dollars per share) $ 0.001                
Sale of stock, price per share (in dollars per share) 49.00                
Underwriting discounts and commissions (in dollars per share) $ 2.45                
Sale of stock, consideration received $ 218,300,000                
Subsequent Event | Over-Allotment Option                  
Subsequent Event [Line Items]                  
Number of shares issued in transaction 612,244                
Subsequent Event | Capped Call Transactions                  
Subsequent Event [Line Items]                  
Sale of stock, price per share (in dollars per share)               $ 85.75  
Proceeds from issuance of convertible debt, net of issuance costs $ 29,300,000                
Premium on offering price (as a percent)               75.00%  
Public offering price (in dollars per share)               $ 49.00