UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D/A

Under the Securities Exchange Act of 1934

(Amendment No. 1)*

NeoGenomics, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

64049M209

(CUSIP Number)

Stephen Kanousky

General Counsel, GE Healthcare Life Sciences

General Electric Company

350 Campus Drive

Marlborough, Massachusetts 01752-3082

(414) 721-2200

With a copy to:

Stephen D. Cooke

Paul Hastings LLP

695 Town Center Drive, Seventeenth Floor

Costa Mesa, CA 92926

(714) 668-6264

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

December 21, 2015

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.  ¨

NOTE: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7(b) for other parties to whom copies are to be sent.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

EXPLANATORY NOTE

This Amendment No. 1 (this “Amendment No. 1”) amends and supplements the statement on Schedule 13D (the “Original Schedule 13D”) jointly filed with the Securities and Exchange Commission (the “SEC”) on October 30, 2015 by (i) General Electric Company, a New York corporation (“General Electric”), (ii) GE Medical Systems Information Technologies, Inc., a Wisconsin corporation (“GE InfoTech”) and (iii) GE Medical Holding AB, a private limited company (privat aktiebolag) organized under the laws of the Kingdom of Sweden (Reg. No. 556648-9315) (“GE Medical”), relating to the common stock, par value $0.001 per share (“Common Shares”), of NeoGenomics, Inc., a Nevada corporation (“NeoGenomics”). As described in the Original Schedule 13D, GE Medical is a wholly owned subsidiary of GE InfoTech, which is in turn a wholly owned subsidiary of General Electric.

The Original Schedule 13D was filed by General Electric, GE InfoTech and GE Medical (collectively the “GE Parties”) to report beneficial ownership of approximately 7.7% of the outstanding Common Shares solely because GE Medical entered into individual Voting Agreements, dated as of October 20, 2015 (collectively, the “Voting Agreements”), with each of the executive officers and directors of NeoGenomics listed on Schedule B to the Original Schedule 13D (the “Supporting Stockholders”). The Voting Agreements were entered into in connection with GE Medical’s entry into a Stock Purchase Agreement, dated as of October 20, 2015 (the “Purchase Agreement”), with NeoGenomics and NeoGenomics Laboratories, Inc., a wholly owned subsidiary of NeoGenomics (“NeoGenomics Laboratories”), pursuant to which NeoGenomics (through NeoGenomics Laboratories) agreed to acquire from GE Medical all of the issued and outstanding shares of common stock, par value $0.01 per share, of Clarient, Inc., a wholly owned subsidiary of GE Medical, in exchange for (i) cash consideration of $80.0 million, (ii) 15,000,000 Common Shares and (iii) 14,666,667 shares of Series A convertible preferred stock, par value $0.001 per share (“Preferred Shares”), of NeoGenomics, as such number of Preferred Shares may be adjusted pursuant to the terms of the Purchase Agreement (collectively, the “Transaction”).

This Amendment No. 1 is being filed by the GE Parties because, on December 21, 2015, the stockholders of NeoGenomics approved at a special meeting of stockholders various proposals related to the Transaction (such proposals are referred to herein as the “Transaction Proposals”). As a result of the approval of the Transaction Proposals, the Voting Agreements terminated on December 21, 2015 in accordance with their terms. Upon the termination of the Voting Agreements, none of the GE Parties has beneficial ownership over any Common Shares (including Common Shares underlying unexercised options, warrants and other rights) owned by the Supporting Stockholders and previously subject to the Voting Agreements.

Pursuant to Rule 13d-4 of the Exchange Act, each of the GE Parties expressly declares that neither the filing of this Amendment No. 1 or the Original Schedule 13D, nor any of their respective contents, shall be deemed to constitute an admission by General Electric, GE InfoTech or GE Medical, as applicable, that it is or was the beneficial owner of any of the Common Shares held by the Supporting Stockholders for purposes of Section 13(d) or 13(g) of the Exchange Act, or for any other purpose, and such beneficial ownership is expressly disclaimed.

Except as specifically provided herein, this Amendment No. 1 does not modify any of the information previously reported in the Original Schedule 13D. Any capitalized terms used in this Amendment No. 1 and not otherwise defined herein shall have the respective meanings ascribed to such terms in the Original Schedule 13D.

There has been no change to the information disclosed in Item 1 of the Original Schedule 13D.

Schedule A to this Amendment No. 1 is hereby amended and restated in the form attached hereto, which is incorporated herein by reference. In all other respects, there has been no change to the information disclosed in Item 2 of the Original Schedule 13D.

There has been no change to the information disclosed in Item 3 of the Original Schedule 13D.

The section “Voting Agreements” in Item 4 of the Original Schedule 13D is hereby amended to add the following paragraph:

On December 21, 2015, NeoGenomics stockholders approved the Transaction Proposals which in turn resulted in the termination of the Voting Agreements in accordance with their terms.

Item 5 of the Original Schedule 13D is hereby amended and restated as follows:

(a)-(b), (e) As a result of the termination of the Voting Agreements, on December 21, 2015, the GE Parties ceased to have beneficial ownership over any Common Shares; therefore, none of the GE Parties has voting or dispositive power over any Common Shares.

In addition, to the best of each of GE Parties’ knowledge, each of its executive officers and directors does not beneficially own any Common Shares.

(c) Except as otherwise disclosed herein, each of GE Parties has not, and, to the best of each of GE Parties’ knowledge, each of the persons listed in Schedule A hereto has not, effected any transaction in Common Shares during the past 60 days.

(d) Not applicable.

There has been no change to the information disclosed in Item 6 of the Original Schedule 13D.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: December 23, 2015

SCHEDULE A

DIRECTORS AND EXECUTIVE OFFICERS OF GENERAL ELECTRIC COMPANY

The name, citizenship, business address, and present principal occupation or employment of each of the directors and executive officers of General Electric Company are set forth below. The business address of each director and executive officer of General Electric Company is 3135 Easton Turnpike, Fairfield, Connecticut 06828-0001. All of the individuals listed below are citizens of the United States of America other than W. Geoffrey Beattie and Andrea Jung, who are citizens of Canada. Marijin E. Dekkers is also a citizen of the Netherlands.

DIRECTORS AND EXECUTIVE OFFICERS OF GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC.

The name, citizenship, business address, and present principal occupation or employment of each of the directors and executive officers of GE Medical Systems Information Technologies, Inc. are set forth below. The business address of each director and executive officer of GE Medical Systems Information Technologies, Inc. is 8200 West Tower Avenue, Milwaukee, Wisconsin 53223. Thierry Leclercq is a citizen of France and Peter Logan is a citizen of the United States of America.

DIRECTORS AND EXECUTIVE OFFICERS OF GE MEDICAL HOLDING AB

The name, citizenship, business address, and present principal occupation or employment of each of the directors and executive officers of GE Medical Holding AB are set forth below. The business address of each director and executive officer of GE Medical Holding AB is Björkgatan 30, 75184 Uppsala, Sweden. Nathan Winters is a citizen of the United States of America, Martin Wilkinson is a citizen of the United Kingdom, and Jan Erneberg and Ann-Christine Löfgren are citizens of Sweden.

INDEX OF EXHIBITS